Polyphenolic Biflavonoids Inhibit Amyloid-Beta Fibrillation and Disaggregate Preformed Amyloid-Beta Fibrils
نویسندگان
چکیده
منابع مشابه
Graphene oxide strongly inhibits amyloid beta fibrillation.
UNLABELLED Since amyloid beta fibrillation (AβF) plays an important role in the development of neurodegenerative diseases, we investigated the effect of graphene oxide (GO) and their protein-coated surfaces on the kinetics of Aβ fibrillation in the aqueous solution. We showed that GO and their protein-covered surfaces delay the AβF process via adsorption of amyloid monomers. Also, the large ava...
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ژورنال
عنوان ژورنال: Biomolecules & Therapeutics
سال: 2020
ISSN: 1976-9148,2005-4483
DOI: 10.4062/biomolther.2019.113